Chromatography Standards
![Medchemexpress LLC N-[3-[[5-chloro-2-[[4-(4-methyl-1-piperazinyl)phenyl]amino]-4-pyrimidinyl]thio]phenyl]-2-propenamide | 1214265-57-2 | 99.2% | 5 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000234411.png-250.jpg)
Medchemexpress LLC N-[3-[[5-chloro-2-[[4-(4-methyl-1-piperazinyl)phenyl]amino]-4-pyrimidinyl]thio]phenyl]-2-propenamide | 1214265-57-2 | 99.2% | 5 MG
WZ8040 is an irreversible, mutant-selective inhibitor of the epidermal growth factor receptor (EGFR) with activity against the T790M resistance mutation. It inhibits EGFR phosphorylation and is used as a laboratory research compound to study mutant EGFR signaling and inhibitor sensitivity.
- Irreversible inhibitor of EGFR T790M.
- Demonstrates substantially greater potency against mutant EGFR compared with wild-type.
- Available as solid powder and as DMSO solutions for ready-to-use applications.
- Typical purity around 99.2% as supplied.
- Soluble in DMSO (high solubility reported) and formulatable for in vivo dosing protocols.
- Store powder at -20°C for long-term stability; store stock solutions at -80°C when possible.
- Intended for research use only; not for human or veterinary use.
Medchemexpress LLC Tolazamide | 1156-19-0 | 99.9% | 5 MG
Tolazamide (U-17835) is an orally active sulfonylurea agent that inhibits sulfonylurea receptor 1 (SUR1) linked to the inwardly rectifying potassium channel (IC50 = 4.2 μM in HEK293 cells transfected with the human receptor). It has anti-diabetic properties, lowering blood glucose and decreasing insulin dose while maintaining adequate metabolic control. Tolazamide can also improve or normalize hyperglycemia and HbA.
- Orally active sulfonylurea agent
- Inhibits sulfonylurea receptor 1 (SUR1)
- Lowers blood glucose
- Decreases insulin dose
- Maintains metabolic control
- Improves or normalizes hyperglycemia and HbA
- Attenuates gluconeogenesis and ketogenesis
Sigma Aldrich Fine Chemicals Biosciences Emetine dihydrochloride50MG
hydrochloride Emetine dihydrochloride50MG
Medchemexpress LLC Diclofenac (diethylamine) | 78213-16-8 | C18H22Cl2N2O2 | 5 G
Diclofenac diethylamine is a potent and nonselective anti-inflammatory agent that acts as a COX inhibitor. It has IC50s of 4 and 1.3 nM for human COX-1 and COX-2 in CHO cells, and 5.1 and 0.84 μM for ovine COX-1 and COX-2, respectively. Additionally, it induces apoptosis of neural stem cells (NSCs) by activating the caspase cascade.
- Potent and nonselective anti-inflammatory agent: acts as a COX inhibitor.
- Target specificities: IC50s of 4 nM for human COX-1 and 1.3 nM for human COX-2 in CHO cells.
- Ovine COX inhibition: IC50s of 5.1 μM for ovine COX-1 and 0.84 μM for ovine COX-2.
- Apoptosis induction: induces apoptosis of neural stem cells (NSCs) via activation of the caspase cascade.
- Available in 5 G variant.
Sigma Aldrich Fine Chemicals Biosciences Lamotrigine impurity E European Pharmacopoeia (EP) Reference Standard | 50-45-3 | MFCD00002413 |
Lamotrigine impurity E European Pharmacopoeia (EP) Reference Standard | Mol Wt: 191.01 | 50-45-3 | MFCD00002413 |
Sigma Aldrich Fine Chemicals Biosciences Lanolin alcohols United States Pharmacopeia (USP) Reference Standard | 8027-33-6 | 5G
Lanolin alcohols United States Pharmacopeia (USP) Reference Standard | 8027-33-6 | 5G
![eMolecules 183133-96-2 | Cabazitaxel | TargetMol | MFCD18827611 | 835.944 | C45H57NO14 | 0.000 | CO[C@H]1C[C@H]2OC[C@@]2(OC(C)=O)[C@H]2[C@H](OC(=O)c3ccccc3)[C@]3(O)C[C@H](OC(=O)[C@H](O)[C@@H](NC(=O)OC(C)(C)C)c4ccccc4)C(C)=C([C@@H](OC)C(=O)[C@]12C)C3(C)C | 20mg | 779730313](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000191062.jpg-250.jpg)
eMolecules 183133-96-2 | Cabazitaxel | TargetMol | MFCD18827611 | 835.944 | C45H57NO14 | 0.000 | CO[C@H]1C[C@H]2OC[C@@]2(OC(C)=O)[C@H]2[C@H](OC(=O)c3ccccc3)[C@]3(O)C[C@H](OC(=O)[C@H](O)[C@@H](NC(=O)OC(C)(C)C)c4ccccc4)C(C)=C([C@@H](OC)C(=O)[C@]12C)C3(C)C | 20mg | 779730313
Cabazitaxel | TargetMol | 183133-96-2 | MFCD18827611 | 835.944 | C45H57NO14 | 0.000 | CO[C@H]1C[C@H]2OC[C@@]2(OC(C)=O)[C@H]2[C@H](OC(=O)c3ccccc3)[C@]3(O)C[C@H](OC(=O)[C@H](O)[C@@H](NC(=O)OC(C)(C)C)c4ccccc4)C(C)=C([C@@H](OC)C(=O)[C@]12C)C3(C)C | 20mg | 779730313
Medchemexpress LLC (3S,4S)-Tivantinib | 905854-03-7 | C23H19N3O2 | 1 ML
(3S,4S)-Tivantinib is a potent and highly selective inhibitor of the receptor tyrosine kinase c-MET. It also targets GSK3α and GSK3β, which play an important role in the cellular mechanism of non-small cell lung cancer (NSCLC).
- Potent and highly selective inhibitor of c-MET
- Targets GSK3α and GSK3β
- Relevant for non-small cell lung cancer (NSCLC) research